Drug interactions
Betaxolol + Lorcaserin
Severity: Minor
Betaxolol and Lorcaserin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lorcaserin inhibits CYP2D6 and may raise exposure to CYP2D6 substrates. Betaxolol is metabolized partly by CYP2D6 but also by other pathways, so the effect is probably modest.
What this interaction means in plain words
Betaxolol and Lorcaserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Lorcaserin inhibits CYP2D6-mediated metabolism of betaxolol.
What to do
Monitor heart rate and blood pressure for signs of excess beta-blockade. Adjust the betaxolol dose if bradycardia or hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Lorcaserin?
MediHelp rates the interaction as minor. Betaxolol and Lorcaserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lorcaserin inhibits CYP2D6 and may raise exposure to CYP2D6 substrates. Betaxolol is metabolized partly by CYP2D6 but also by other pathways, so the effect is probably modest.
How serious is the interaction between Betaxolol and Lorcaserin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure for signs of excess beta-blockade. Adjust the betaxolol dose if bradycardia or hypotension develops.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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