Drug interactions
Betaxolol + Terbutaline
Severity: Moderate
Betaxolol and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol can blunt the bronchodilating effect of terbutaline and may cause bronchospasm in patients with reactive airway disease. The risk is lower than with non-selective agents but remains, particularly at higher doses or with systemic absorption from ophthalmic use.
What this interaction means in plain words
Betaxolol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Terbutaline belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism at beta-2 receptors by a beta-1 selective blocker whose selectivity is dose-dependent.
What to do
Use the lowest effective betaxolol dose in patients with asthma or COPD, or select a non-beta-blocker alternative. Monitor respiratory function and terbutaline requirements.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Terbutaline?
MediHelp rates the interaction as moderate. Betaxolol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol can blunt the bronchodilating effect of terbutaline and may cause bronchospasm in patients with reactive airway disease. The risk is lower than with non-selective agents but remains, particularly at higher doses or with systemic absorption from ophthalmic use.
How serious is the interaction between Betaxolol and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective betaxolol dose in patients with asthma or COPD, or select a non-beta-blocker alternative. Monitor respiratory function and terbutaline requirements.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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