Drug interactions
Betaxolol + Theophylline
Severity: Moderate
Betaxolol and Theophylline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol is cardioselective and may counteract theophylline bronchodilation, especially at higher doses or in patients with reactive airways. Theophylline levels are only slightly affected by selective agents.
What this interaction means in plain words
Betaxolol and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Theophylline belongs to Respiratory.
Why it happens
Beta-2 receptor antagonism opposes bronchodilation; possible minor reduction in theophylline metabolism.
What to do
Use the lowest effective betaxolol dose and monitor for bronchospasm and theophylline toxicity.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Theophylline?
MediHelp rates the interaction as moderate. Betaxolol and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol is cardioselective and may counteract theophylline bronchodilation, especially at higher doses or in patients with reactive airways. Theophylline levels are only slightly affected by selective agents.
How serious is the interaction between Betaxolol and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective betaxolol dose and monitor for bronchospasm and theophylline toxicity.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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