Drug interactions
Betrixaban + Citalopram
Severity: Moderate
Betrixaban and Citalopram: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citalopram impairs platelet function and betrixaban is a factor Xa inhibitor anticoagulant. Together they increase the risk of clinically significant bleeding.
What this interaction means in plain words
Betrixaban and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effects on hemostasis: SSRI-induced platelet dysfunction plus factor Xa inhibition.
What to do
Monitor for signs of bleeding and check hemoglobin periodically. Reassess the need for the SSRI in patients at high bleeding risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Betrixaban with Citalopram?
MediHelp rates the interaction as moderate. Betrixaban and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Citalopram impairs platelet function and betrixaban is a factor Xa inhibitor anticoagulant. Together they increase the risk of clinically significant bleeding.
How serious is the interaction between Betrixaban and Citalopram?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of bleeding and check hemoglobin periodically. Reassess the need for the SSRI in patients at high bleeding risk.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
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