Drug interactions
Bisoprolol + Calcium chloride
Severity: Minor
Bisoprolol and Calcium chloride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous calcium has positive inotropic effects and can transiently reduce the effects of beta-blockers. This is mainly a consideration in the treatment of beta-blocker overdose.
What this interaction means in plain words
Bisoprolol and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Increased intracellular calcium counteracts negative inotropy and chronotropy from beta-blockade.
What to do
No routine action is needed. Monitor heart rate and blood pressure if calcium is given intravenously to a patient on bisoprolol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Calcium chloride?
MediHelp rates the interaction as minor. Bisoprolol and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous calcium has positive inotropic effects and can transiently reduce the effects of beta-blockers. This is mainly a consideration in the treatment of beta-blocker overdose.
How serious is the interaction between Bisoprolol and Calcium chloride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor heart rate and blood pressure if calcium is given intravenously to a patient on bisoprolol.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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