Drug interactions
Bisoprolol + Fenoldopam
Severity: Moderate
Bisoprolol and Fenoldopam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenoldopam is a rapidly acting vasodilator, and combining it with beta-blockers can cause excess hypotension. Beta-blockers may also blunt reflex tachycardia, hiding early warning signs.
What this interaction means in plain words
Bisoprolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotension from dopamine-1 agonist vasodilation and beta-blockade.
What to do
Monitor blood pressure continuously during infusion and titrate fenoldopam carefully. Avoid concurrent beta-blocker use where possible during acute infusion.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Fenoldopam?
MediHelp rates the interaction as moderate. Bisoprolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenoldopam is a rapidly acting vasodilator, and combining it with beta-blockers can cause excess hypotension. Beta-blockers may also blunt reflex tachycardia, hiding early warning signs.
How serious is the interaction between Bisoprolol and Fenoldopam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure continuously during infusion and titrate fenoldopam carefully. Avoid concurrent beta-blocker use where possible during acute infusion.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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