Drug interactions
Bisoprolol + Hydrochlorothiazide-olmesartan
Severity: Minor
Bisoprolol and Hydrochlorothiazide-olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bisoprolol with olmesartan and hydrochlorothiazide lowers blood pressure additively, which can cause hypotension or bradycardia. This is a commonly used combination and is usually well tolerated.
What this interaction means in plain words
Bisoprolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bisoprolol belongs to Cardiovascular; Hydrochlorothiazide-olmesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects of beta blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate after initiation or dose changes. Check potassium periodically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Hydrochlorothiazide-olmesartan?
MediHelp rates the interaction as minor. Bisoprolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bisoprolol with olmesartan and hydrochlorothiazide lowers blood pressure additively, which can cause hypotension or bradycardia. This is a commonly used combination and is usually well tolerated.
How serious is the interaction between Bisoprolol and Hydrochlorothiazide-olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate after initiation or dose changes. Check potassium periodically.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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