Drug interactions
Bisoprolol + Ketorolac
Severity: Minor
Bisoprolol and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac may weaken the blood pressure lowering effect of bisoprolol, particularly with sustained use. The effect is usually modest.
What this interaction means in plain words
Bisoprolol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bisoprolol belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
Why it happens
NSAID inhibition of vasodilatory prostaglandins and sodium and water retention oppose the antihypertensive action of the beta-blocker.
What to do
Monitor blood pressure if ketorolac is used beyond a few days. Adjust antihypertensive therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Ketorolac?
MediHelp rates the interaction as minor. Bisoprolol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ketorolac may weaken the blood pressure lowering effect of bisoprolol, particularly with sustained use. The effect is usually modest.
How serious is the interaction between Bisoprolol and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if ketorolac is used beyond a few days. Adjust antihypertensive therapy if needed.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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