Drug interactions
Bisoprolol + Levobetaxolol
Severity: Moderate
Bisoprolol and Levobetaxolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levobetaxolol is a beta-blocker given as an eye drop, and systemic absorption can add to the beta-blockade of oral bisoprolol. This may deepen bradycardia or lower blood pressure, especially in older patients or those with conduction disease.
What this interaction means in plain words
Bisoprolol and Levobetaxolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic receptor blockade from systemically absorbed ophthalmic levobetaxolol and oral bisoprolol.
What to do
Monitor heart rate and blood pressure when starting or adjusting the ophthalmic beta-blocker. Consider a non-beta-blocker glaucoma agent if bradycardia or hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Levobetaxolol?
MediHelp rates the interaction as moderate. Bisoprolol and Levobetaxolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levobetaxolol is a beta-blocker given as an eye drop, and systemic absorption can add to the beta-blockade of oral bisoprolol. This may deepen bradycardia or lower blood pressure, especially in older patients or those with conduction disease.
How serious is the interaction between Bisoprolol and Levobetaxolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting or adjusting the ophthalmic beta-blocker. Consider a non-beta-blocker glaucoma agent if bradycardia or hypotension develops.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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