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Drug interactions

Bivalirudin + Ginko biloba

Severity: Moderate

Bivalirudin and Ginko biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Bivalirudin is a direct thrombin inhibitor, and ginkgo may impair platelet function. Combined use may increase bleeding risk, mainly in the procedural setting where bivalirudin is typically given.

What this interaction means in plain words

Bivalirudin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive effects of direct thrombin inhibition and ginkgolide inhibition of platelet-activating factor.

What to do

Ask about ginkgo use before invasive procedures and withhold it beforehand. Monitor for bleeding and clotting time as appropriate.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bivalirudin with Ginko biloba?

MediHelp rates the interaction as moderate. Bivalirudin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bivalirudin is a direct thrombin inhibitor, and ginkgo may impair platelet function. Combined use may increase bleeding risk, mainly in the procedural setting where bivalirudin is typically given.

How serious is the interaction between Bivalirudin and Ginko biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about ginkgo use before invasive procedures and withhold it beforehand. Monitor for bleeding and clotting time as appropriate.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

Full monographs, dosing and an interaction checker in the MediHelp app

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