Drug interactions
Bretylium + Telmisartan
Severity: Moderate
Bretylium and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause hypotension, so the combination may produce excessive blood pressure reduction. Bretylium is used in emergencies, so hypotension can be clinically important.
What this interaction means in plain words
Bretylium and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotensive effects from sympathetic blockade and angiotensin receptor blockade.
What to do
Monitor blood pressure continuously during bretylium use and hold or reduce telmisartan if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Bretylium with Telmisartan?
MediHelp rates the interaction as moderate. Bretylium and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause hypotension, so the combination may produce excessive blood pressure reduction. Bretylium is used in emergencies, so hypotension can be clinically important.
How serious is the interaction between Bretylium and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure continuously during bretylium use and hold or reduce telmisartan if hypotension occurs.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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