Drug interactions
Brivaracetam + Ethanol
Severity: Moderate
Brivaracetam and Ethanol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol taken with brivaracetam enhanced CNS depressant effects in controlled studies, with measurable impairment of psychomotor performance and alertness. This may impair driving and increase accident risk.
What this interaction means in plain words
Brivaracetam and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression; alcohol also appeared to increase brivaracetam exposure only modestly.
What to do
Advise patients to avoid alcohol or keep intake minimal while taking brivaracetam. Counsel against driving after drinking.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Ethanol?
MediHelp rates the interaction as moderate. Brivaracetam and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol taken with brivaracetam enhanced CNS depressant effects in controlled studies, with measurable impairment of psychomotor performance and alertness. This may impair driving and increase accident risk.
How serious is the interaction between Brivaracetam and Ethanol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol or keep intake minimal while taking brivaracetam. Counsel against driving after drinking.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Acetaminophen / phenyltoloxamine. The full list is on the Brivaracetam page.
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