Drug interactions
Brivaracetam + Ketamine
Severity: Minor
Brivaracetam and Ketamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brivaracetam commonly causes somnolence and dizziness. Used with ketamine, it may add to sedation and impaired coordination.
What this interaction means in plain words
Brivaracetam and Ketamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brivaracetam belongs to Central Nervous System; Ketamine belongs to Central Nervous System.
Why it happens
Additive CNS depression through different mechanisms (SV2A ligand and NMDA antagonism).
What to do
Monitor sedation and continue anticonvulsant therapy as prescribed; titrate ketamine to effect.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketamine
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Ketamine?
MediHelp rates the interaction as minor. Brivaracetam and Ketamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brivaracetam commonly causes somnolence and dizziness. Used with ketamine, it may add to sedation and impaired coordination.
How serious is the interaction between Brivaracetam and Ketamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation and continue anticonvulsant therapy as prescribed; titrate ketamine to effect.
What other medicines interact with Ketamine?
MediHelp also lists interactions of Ketamine with, for example, Benzhydrocodone / acetaminophen, Brexanolone, Buprenorphine buccal. The full list is on the Ketamine page.
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