Drug interactions
Brivaracetam + Opium tincture
Severity: Moderate
Brivaracetam and Opium tincture: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opium tincture contains morphine and other opioid alkaloids that cause sedation and respiratory depression. Brivaracetam adds to CNS depression, so the pair can cause excessive drowsiness.
What this interaction means in plain words
Brivaracetam and Opium tincture can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression from opioid receptor agonism and brivaracetam's central effects.
What to do
Monitor sedation and respiratory rate, particularly when doses are started or raised. Avoid alcohol and other depressants.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Opium tincture?
MediHelp rates the interaction as moderate. Brivaracetam and Opium tincture can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Opium tincture contains morphine and other opioid alkaloids that cause sedation and respiratory depression. Brivaracetam adds to CNS depression, so the pair can cause excessive drowsiness.
How serious is the interaction between Brivaracetam and Opium tincture?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation and respiratory rate, particularly when doses are started or raised. Avoid alcohol and other depressants.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Acetaminophen / phenyltoloxamine. The full list is on the Brivaracetam page.
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