Drug interactions
Brivaracetam + Pimozide
Severity: Moderate
Brivaracetam and Pimozide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence, dizziness and impaired coordination. Used together, central nervous system effects may be additive, especially during dose initiation or titration.
What this interaction means in plain words
Brivaracetam and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Pimozide belongs to Central Nervous System.
Why it happens
Additive central nervous system depressant effects.
What to do
Monitor for excessive sedation and dizziness when starting or increasing either drug. Advise patients to avoid driving until the response is known.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pimozide
- Adagrasib + Pimozide Contraindicated
- Amiodarone + Pimozide Contraindicated
- Amisulpride + Pimozide Contraindicated
- Amitriptyline + Pimozide Contraindicated
- Amoxapine + Pimozide Contraindicated
- Anagrelide + Pimozide Contraindicated
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Pimozide?
MediHelp rates the interaction as moderate. Brivaracetam and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause somnolence, dizziness and impaired coordination. Used together, central nervous system effects may be additive, especially during dose initiation or titration.
How serious is the interaction between Brivaracetam and Pimozide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and dizziness when starting or increasing either drug. Advise patients to avoid driving until the response is known.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
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