Drug interactions
Budesonide + Choline magnesium trisalicylate
Severity: Moderate
Budesonide and Choline magnesium trisalicylate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids combined with salicylates raise the risk of gastrointestinal irritation, ulceration and bleeding. Corticosteroids may also lower salicylate levels and salicylate levels can rise when steroids are withdrawn. Budesonide's low systemic exposure reduces but does not eliminate the concern.
What this interaction means in plain words
Budesonide and Choline magnesium trisalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive gastrointestinal mucosal injury from prostaglandin inhibition and impaired mucosal healing.
What to do
Use the lowest effective salicylate dose, consider gastroprotection in high-risk patients, and monitor for GI bleeding symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Choline magnesium trisalicylate?
MediHelp rates the interaction as moderate. Budesonide and Choline magnesium trisalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids combined with salicylates raise the risk of gastrointestinal irritation, ulceration and bleeding. Corticosteroids may also lower salicylate levels and salicylate levels can rise when steroids are withdrawn. Budesonide's low systemic exposure reduces but does not eliminate the concern.
How serious is the interaction between Budesonide and Choline magnesium trisalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective salicylate dose, consider gastroprotection in high-risk patients, and monitor for GI bleeding symptoms.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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