Drug interactions
Budesonide + Dabrafenib
Severity: Moderate
Budesonide and Dabrafenib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dabrafenib induces CYP3A4 and may lower systemic and possibly local budesonide exposure. This could reduce budesonide effectiveness.
What this interaction means in plain words
Budesonide and Dabrafenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Dabrafenib belongs to Oncology.
Why it happens
Dabrafenib induces CYP3A4, accelerating budesonide metabolism.
What to do
Monitor for reduced budesonide response and increase the dose if needed. Reassess if dabrafenib is stopped.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Other interactions of Dabrafenib
Frequently asked questions
Can I take Budesonide with Dabrafenib?
MediHelp rates the interaction as moderate. Budesonide and Dabrafenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dabrafenib induces CYP3A4 and may lower systemic and possibly local budesonide exposure. This could reduce budesonide effectiveness.
How serious is the interaction between Budesonide and Dabrafenib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced budesonide response and increase the dose if needed. Reassess if dabrafenib is stopped.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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