Drug interactions
Budesonide + Deferasirox
Severity: Moderate
Budesonide and Deferasirox: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox can cause gastric ulceration and gastrointestinal hemorrhage, and corticosteroids may add to this risk. Deferasirox may also induce CYP3A4 modestly, which could lower budesonide exposure.
What this interaction means in plain words
Budesonide and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Deferasirox belongs to Miscellaneous.
Why it happens
Additive gastrointestinal mucosal toxicity, plus possible CYP3A4 induction by deferasirox.
What to do
Monitor for GI bleeding symptoms and consider gastroprotection; watch for reduced budesonide efficacy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Other interactions of Deferasirox
Frequently asked questions
Can I take Budesonide with Deferasirox?
MediHelp rates the interaction as moderate. Budesonide and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox can cause gastric ulceration and gastrointestinal hemorrhage, and corticosteroids may add to this risk. Deferasirox may also induce CYP3A4 modestly, which could lower budesonide exposure.
How serious is the interaction between Budesonide and Deferasirox?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI bleeding symptoms and consider gastroprotection; watch for reduced budesonide efficacy.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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