Drug interactions
Budesonide + Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine
Severity: Minor
Budesonide and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroid therapy may reduce the immune response to this inactivated combination vaccine. It does not cause infection, so the concern is reduced protection only.
What this interaction means in plain words
Budesonide and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid immunosuppression can reduce antibody production after vaccination.
What to do
Proceed with vaccination on schedule; consider assessing response or giving extra doses if the patient is on prolonged high-dose systemic steroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates the interaction as minor. Budesonide and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroid therapy may reduce the immune response to this inactivated combination vaccine. It does not cause infection, so the concern is reduced protection only.
How serious is the interaction between Budesonide and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Proceed with vaccination on schedule; consider assessing response or giving extra doses if the patient is on prolonged high-dose systemic steroids.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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