Drug interactions
Budesonide + Diphtheria and tetanus toxoids / acellular pertussis vaccine
Severity: Minor
Budesonide and Diphtheria and tetanus toxoids / acellular pertussis vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may blunt antibody responses to this inactivated combination vaccine. There is no infection risk because it contains no live organisms.
What this interaction means in plain words
Budesonide and Diphtheria and tetanus toxoids / acellular pertussis vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid immunosuppression can reduce antibody production after vaccination.
What to do
Vaccinate as scheduled; for patients on high-dose systemic steroids consider timing doses when the steroid dose is lowest or reviewing immunity later.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Diphtheria and tetanus toxoids / acellular pertussis vaccine?
MediHelp rates the interaction as minor. Budesonide and Diphtheria and tetanus toxoids / acellular pertussis vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may blunt antibody responses to this inactivated combination vaccine. There is no infection risk because it contains no live organisms.
How serious is the interaction between Budesonide and Diphtheria and tetanus toxoids / acellular pertussis vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as scheduled; for patients on high-dose systemic steroids consider timing doses when the steroid dose is lowest or reviewing immunity later.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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