Drug interactions
Budesonide + Glecaprevir / pibrentasvir
Severity: Minor
Budesonide and Glecaprevir / pibrentasvir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glecaprevir and pibrentasvir inhibit P-glycoprotein and may modestly raise systemic budesonide exposure. The clinical significance is likely small, especially with inhaled or locally acting forms.
What this interaction means in plain words
Budesonide and Glecaprevir / pibrentasvir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of intestinal P-glycoprotein efflux increases budesonide absorption.
What to do
No routine adjustment is needed; watch for signs of corticosteroid excess if oral budesonide is used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide and Glecaprevir / pibrentasvir, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Glecaprevir / pibrentasvir?
MediHelp rates the interaction as minor. Budesonide and Glecaprevir / pibrentasvir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glecaprevir and pibrentasvir inhibit P-glycoprotein and may modestly raise systemic budesonide exposure. The clinical significance is likely small, especially with inhaled or locally acting forms.
How serious is the interaction between Budesonide and Glecaprevir / pibrentasvir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; watch for signs of corticosteroid excess if oral budesonide is used long term.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
