Drug interactions
Budesonide + Hepatitis b vaccine
Severity: Minor
Budesonide and Hepatitis b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may reduce seroconversion after hepatitis B vaccination, particularly at higher systemic doses. The vaccine is non-live, so it remains safe to give.
What this interaction means in plain words
Budesonide and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid immunosuppression can reduce antibody production after vaccination.
What to do
Vaccinate as indicated and check anti-HBs after completing the series in patients on prolonged systemic therapy or with risk factors; revaccinate if non-responsive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Hepatitis b vaccine?
MediHelp rates the interaction as minor. Budesonide and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may reduce seroconversion after hepatitis B vaccination, particularly at higher systemic doses. The vaccine is non-live, so it remains safe to give.
How serious is the interaction between Budesonide and Hepatitis b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as indicated and check anti-HBs after completing the series in patients on prolonged systemic therapy or with risk factors; revaccinate if non-responsive.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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