Drug interactions
Budesonide + Measles vaccine
Severity: Major
Budesonide and Measles vaccine: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Live measles vaccine given during immunosuppressive corticosteroid therapy may cause uncontrolled vaccine-virus replication and may produce a weaker immune response. The risk is mainly with systemic or high-dose treatment.
What this interaction means in plain words
Budesonide and Measles vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Corticosteroid suppression of cell-mediated immunity impairs control of live attenuated virus.
What to do
Avoid in patients on immunosuppressive budesonide doses; defer vaccination until steroids are stopped for the labeled interval. Low-dose inhaled or topical use is generally not a barrier.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Measles vaccine?
MediHelp rates the interaction as major. Budesonide and Measles vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live measles vaccine given during immunosuppressive corticosteroid therapy may cause uncontrolled vaccine-virus replication and may produce a weaker immune response. The risk is mainly with systemic or high-dose treatment.
How serious is the interaction between Budesonide and Measles vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive budesonide doses; defer vaccination until steroids are stopped for the labeled interval. Low-dose inhaled or topical use is generally not a barrier.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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