Drug interactions
Budesonide + Somatrem
Severity: Moderate
Budesonide and Somatrem: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can inhibit the growth-promoting effects of growth hormone products such as somatrem. This is most relevant in children receiving growth hormone, particularly with higher or prolonged steroid exposure.
What this interaction means in plain words
Budesonide and Somatrem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism, as glucocorticoids suppress growth and blunt growth hormone action.
What to do
Use the lowest effective budesonide dose and monitor growth velocity; adjust growth hormone dose if response is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide and Somatrem, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Somatrem?
MediHelp rates the interaction as moderate. Budesonide and Somatrem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids can inhibit the growth-promoting effects of growth hormone products such as somatrem. This is most relevant in children receiving growth hormone, particularly with higher or prolonged steroid exposure.
How serious is the interaction between Budesonide and Somatrem?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective budesonide dose and monitor growth velocity; adjust growth hormone dose if response is inadequate.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
