Drug interactions
Budesonide + Somatropin
Severity: Moderate
Budesonide and Somatropin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucocorticoids can inhibit the growth-promoting effects of somatropin, which matters in children treated for growth failure. Somatropin may also alter glucose tolerance, and corticosteroids add to this.
What this interaction means in plain words
Budesonide and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Somatropin belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism: glucocorticoids suppress growth and reduce IGF-1-mediated effects.
What to do
Use the lowest effective budesonide dose and monitor growth velocity and glucose. Adjust the somatropin dose if growth is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Budesonide with Somatropin?
MediHelp rates the interaction as moderate. Budesonide and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucocorticoids can inhibit the growth-promoting effects of somatropin, which matters in children treated for growth failure. Somatropin may also alter glucose tolerance, and corticosteroids add to this.
How serious is the interaction between Budesonide and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective budesonide dose and monitor growth velocity and glucose. Adjust the somatropin dose if growth is inadequate.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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