Drug interactions
Budesonide + Squill
Severity: Moderate
Budesonide and Squill: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Squill contains cardiac glycosides, and corticosteroids can cause hypokalemia, which increases sensitivity to glycoside toxicity. Arrhythmias are the main concern, particularly with systemic or high-dose budesonide.
What this interaction means in plain words
Budesonide and Squill can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroid-induced potassium loss may potentiate cardiac glycoside toxicity.
What to do
Monitor serum potassium and ECG if used together, and correct hypokalemia promptly. Avoid squill preparations where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Squill?
MediHelp rates the interaction as moderate. Budesonide and Squill can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Squill contains cardiac glycosides, and corticosteroids can cause hypokalemia, which increases sensitivity to glycoside toxicity. Arrhythmias are the main concern, particularly with systemic or high-dose budesonide.
How serious is the interaction between Budesonide and Squill?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and ECG if used together, and correct hypokalemia promptly. Avoid squill preparations where possible.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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