Drug interactions
Budesonide + Typhoid polysaccharide vaccine
Severity: Minor
Budesonide and Typhoid polysaccharide vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Typhoid Vi polysaccharide vaccine is non-live, so no infection risk arises, but immunosuppressive corticosteroid doses may reduce the antibody response. The effect is modest with inhaled or low-dose budesonide.
What this interaction means in plain words
Budesonide and Typhoid polysaccharide vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid immunosuppression may lower antibody response to the vaccine.
What to do
Proceed with vaccination at least 2 weeks before travel when possible. Reinforce food and water hygiene in patients on high-dose systemic steroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Typhoid polysaccharide vaccine?
MediHelp rates the interaction as minor. Budesonide and Typhoid polysaccharide vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Typhoid Vi polysaccharide vaccine is non-live, so no infection risk arises, but immunosuppressive corticosteroid doses may reduce the antibody response. The effect is modest with inhaled or low-dose budesonide.
How serious is the interaction between Budesonide and Typhoid polysaccharide vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Proceed with vaccination at least 2 weeks before travel when possible. Reinforce food and water hygiene in patients on high-dose systemic steroids.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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