Drug interactions
Buprenorphine + Dextroamphetamine
Severity: Minor
Buprenorphine and Dextroamphetamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No well-characterized pharmacokinetic or pharmacodynamic interaction exists between these drugs. Stimulants may partly offset sedation, while overlapping effects on mood and cardiovascular response are not clearly defined.
What this interaction means in plain words
Buprenorphine and Dextroamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Buprenorphine belongs to Musculoskeletal; Dextroamphetamine belongs to Central Nervous System.
Why it happens
No established mechanism.
What to do
No specific adjustment is needed. Monitor clinical response and heart rate or blood pressure as appropriate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Buprenorphine
- Alvimopan + Buprenorphine Contraindicated
- Buprenorphine + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Buprenorphine + Olanzapine / samidorphan Contraindicated
- Buprenorphine + Phenelzine Contraindicated
- Buprenorphine + Pimozide Contraindicated
- Buprenorphine + Thioridazine Contraindicated
Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Buprenorphine with Dextroamphetamine?
MediHelp rates the interaction as minor. Buprenorphine and Dextroamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No well-characterized pharmacokinetic or pharmacodynamic interaction exists between these drugs. Stimulants may partly offset sedation, while overlapping effects on mood and cardiovascular response are not clearly defined.
How serious is the interaction between Buprenorphine and Dextroamphetamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific adjustment is needed. Monitor clinical response and heart rate or blood pressure as appropriate.
What other medicines interact with Buprenorphine?
MediHelp also lists interactions of Buprenorphine with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan. The full list is on the Buprenorphine page.
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