Drug interactions
Butorphanol + Levalbuterol
Severity: Minor
Butorphanol and Levalbuterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levalbuterol is an inhaled beta-agonist with minimal sedative effect, so no meaningful offset of butorphanol sedation is expected. Butorphanol and beta-agonists may both affect heart rate, but no clinically important interaction is established.
What this interaction means in plain words
Butorphanol and Levalbuterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; theoretical opposing effects on arousal.
What to do
No specific action required beyond routine monitoring of sedation and heart rate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Butorphanol
- Butorphanol + Olanzapine / samidorphan Contraindicated
- Butorphanol + Sodium oxybate Contraindicated
- Alfentanil + Butorphanol Major
- Alprazolam + Butorphanol Major
- Alvimopan + Butorphanol Major
- Amobarbital + Butorphanol Major
Frequently asked questions
Can I take Butorphanol with Levalbuterol?
MediHelp rates the interaction as minor. Butorphanol and Levalbuterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levalbuterol is an inhaled beta-agonist with minimal sedative effect, so no meaningful offset of butorphanol sedation is expected. Butorphanol and beta-agonists may both affect heart rate, but no clinically important interaction is established.
How serious is the interaction between Butorphanol and Levalbuterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action required beyond routine monitoring of sedation and heart rate.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.
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