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Drug interactions

Butorphanol + Motherwort

Severity: Minor

Butorphanol and Motherwort: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Motherwort is traditionally regarded as a mild sedative herb. Taken with butorphanol it could add to drowsiness and psychomotor slowing, although clinical data are scarce.

What this interaction means in plain words

Butorphanol and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive CNS depression; the sedative activity of motherwort is not well characterised.

What to do

Ask patients about herbal product use and advise them to avoid driving or hazardous tasks while taking both. Watch for excess sedation after butorphanol doses.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Butorphanol with Motherwort?

MediHelp rates the interaction as minor. Butorphanol and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is traditionally regarded as a mild sedative herb. Taken with butorphanol it could add to drowsiness and psychomotor slowing, although clinical data are scarce.

How serious is the interaction between Butorphanol and Motherwort?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal product use and advise them to avoid driving or hazardous tasks while taking both. Watch for excess sedation after butorphanol doses.

What other medicines interact with Butorphanol?

MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.

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