Drug interactions
Cabergoline + Diethylpropion
Severity: Moderate
Cabergoline and Diethylpropion: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diethylpropion is a sympathomimetic anorectic that can raise blood pressure and heart rate, and cabergoline may add vasoconstrictive or hypertensive effects. The combination may increase cardiovascular strain, particularly in patients with hypertension. Clinical data are limited.
What this interaction means in plain words
Cabergoline and Diethylpropion can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pressor effects from sympathomimetic amine activity and ergoline dopamine agonist vasoconstriction.
What to do
Check blood pressure before and during co-use, and avoid the combination in patients with uncontrolled hypertension or cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cabergoline
Frequently asked questions
Can I take Cabergoline with Diethylpropion?
MediHelp rates the interaction as moderate. Cabergoline and Diethylpropion can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Diethylpropion is a sympathomimetic anorectic that can raise blood pressure and heart rate, and cabergoline may add vasoconstrictive or hypertensive effects. The combination may increase cardiovascular strain, particularly in patients with hypertension. Clinical data are limited.
How serious is the interaction between Cabergoline and Diethylpropion?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood pressure before and during co-use, and avoid the combination in patients with uncontrolled hypertension or cardiovascular disease.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Benperidol, Chlorpromazine, Clarithromycin. The full list is on the Cabergoline page.
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