Drug interactions
Cabergoline + Phendimetrazine
Severity: Moderate
Cabergoline and Phendimetrazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phendimetrazine is a sympathomimetic anorectic that can increase blood pressure and heart rate. Combined with cabergoline, additive pressor and vasoconstrictive effects are possible. The evidence is theoretical.
What this interaction means in plain words
Cabergoline and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pressor effects from sympathomimetic activity and ergoline vasoconstriction.
What to do
Monitor blood pressure regularly and avoid in patients with uncontrolled hypertension.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cabergoline and Phendimetrazine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Cabergoline
Frequently asked questions
Can I take Cabergoline with Phendimetrazine?
MediHelp rates the interaction as moderate. Cabergoline and Phendimetrazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phendimetrazine is a sympathomimetic anorectic that can increase blood pressure and heart rate. Combined with cabergoline, additive pressor and vasoconstrictive effects are possible. The evidence is theoretical.
How serious is the interaction between Cabergoline and Phendimetrazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure regularly and avoid in patients with uncontrolled hypertension.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Benperidol, Chlorpromazine, Clarithromycin. The full list is on the Cabergoline page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
