Drug interactions
Cadexomer iodine + Lithium
Severity: Minor
Cadexomer iodine and Lithium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lithium impairs thyroid hormone release and iodine can also suppress thyroid function, so there is a theoretical additive risk of hypothyroidism. Cadexomer iodine is applied topically to wounds, but absorption can be meaningful with large wounds or prolonged use.
What this interaction means in plain words
Cadexomer iodine and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive inhibition of thyroid hormone synthesis and release by lithium and absorbed iodine.
What to do
Monitor thyroid function if cadexomer iodine is used over large areas or for long periods. Treat hypothyroidism if it develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Cadexomer iodine with Lithium?
MediHelp rates the interaction as minor. Cadexomer iodine and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lithium impairs thyroid hormone release and iodine can also suppress thyroid function, so there is a theoretical additive risk of hypothyroidism. Cadexomer iodine is applied topically to wounds, but absorption can be meaningful with large wounds or prolonged use.
How serious is the interaction between Cadexomer iodine and Lithium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor thyroid function if cadexomer iodine is used over large areas or for long periods. Treat hypothyroidism if it develops.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
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