Drug interactions
Calcium chloride + Ferrous sulfate
Severity: Minor
Calcium chloride and Ferrous sulfate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium can reduce the absorption of iron when both are given together. The effect is a possible reduction in iron response.
What this interaction means in plain words
Calcium chloride and Ferrous sulfate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Calcium competes with iron for intestinal uptake and may form poorly absorbed complexes.
What to do
Separate oral iron from oral calcium by at least 2 hours. Monitor iron indices if iron deficiency persists.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferrous sulfate
Frequently asked questions
Can I take Calcium chloride with Ferrous sulfate?
MediHelp rates the interaction as minor. Calcium chloride and Ferrous sulfate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral calcium can reduce the absorption of iron when both are given together. The effect is a possible reduction in iron response.
How serious is the interaction between Calcium chloride and Ferrous sulfate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral iron from oral calcium by at least 2 hours. Monitor iron indices if iron deficiency persists.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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