Drug interactions
Calcium chloride + Hydrocortisone
Severity: Minor
Calcium chloride and Hydrocortisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. For intravenous calcium chloride used acutely the effect is of little consequence, but over long periods the calcium balance may be affected.
What this interaction means in plain words
Calcium chloride and Hydrocortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroids reduce intestinal calcium absorption and increase renal calcium excretion.
What to do
No action for short-term use. Monitor serum calcium if both are given over a prolonged period.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicated
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contraindicated
- Hydrocortisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Hydrocortisone Major
- Aldesleukin + Hydrocortisone Major
- Aspirin + Hydrocortisone Major
Frequently asked questions
Can I take Calcium chloride with Hydrocortisone?
MediHelp rates the interaction as minor. Calcium chloride and Hydrocortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. For intravenous calcium chloride used acutely the effect is of little consequence, but over long periods the calcium balance may be affected.
How serious is the interaction between Calcium chloride and Hydrocortisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action for short-term use. Monitor serum calcium if both are given over a prolonged period.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Smallpox vaccine live. The full list is on the Hydrocortisone page.
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