Drug interactions
Calcium chloride + Propranolol
Severity: Minor
Calcium chloride and Propranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous calcium has no established important effect on propranolol absorption. Calcium may, however, counteract negative inotropic effects of beta-blockade.
What this interaction means in plain words
Calcium chloride and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not established; calcium may pharmacodynamically oppose beta-blocker negative inotropy.
What to do
No routine action is needed; monitor hemodynamics if calcium is given for beta-blocker toxicity or other indications.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Albuterol + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
Frequently asked questions
Can I take Calcium chloride with Propranolol?
MediHelp rates the interaction as minor. Calcium chloride and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous calcium has no established important effect on propranolol absorption. Calcium may, however, counteract negative inotropic effects of beta-blockade.
How serious is the interaction between Calcium chloride and Propranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor hemodynamics if calcium is given for beta-blocker toxicity or other indications.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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