Drug interactions
Calcium citrate + Diltiazem
Severity: Minor
Calcium citrate and Diltiazem: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium citrate supplements may slightly oppose diltiazem if serum calcium rises. At usual supplemental doses the effect is generally small.
What this interaction means in plain words
Calcium citrate and Diltiazem have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic antagonism: higher extracellular calcium counteracts calcium channel blockade.
What to do
No change is routinely needed. Check serum calcium and blood pressure if large doses are used or response to diltiazem decreases.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diltiazem
- Diltiazem + Flibanserin Contraindicated
- Diltiazem + Ivabradine Contraindicated
- Diltiazem + Lomitapide Contraindicated
- Diltiazem + Lonafarnib Contraindicated
- Acebutolol + Diltiazem Major
- Alfentanil + Diltiazem Major
Frequently asked questions
Can I take Calcium citrate with Diltiazem?
MediHelp rates the interaction as minor. Calcium citrate and Diltiazem have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral calcium citrate supplements may slightly oppose diltiazem if serum calcium rises. At usual supplemental doses the effect is generally small.
How serious is the interaction between Calcium citrate and Diltiazem?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is routinely needed. Check serum calcium and blood pressure if large doses are used or response to diltiazem decreases.
What other medicines interact with Diltiazem?
MediHelp also lists interactions of Diltiazem with, for example, Flibanserin, Ivabradine, Lomitapide. The full list is on the Diltiazem page.
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