Drug interactions
Captopril + Moxisylyte
Severity: Moderate
Captopril and Moxisylyte: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-adrenergic blocker with vasodilating activity. With captopril, an exaggerated blood pressure drop may occur, particularly after the first dose.
What this interaction means in plain words
Captopril and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive vasodilatory and hypotensive effects from alpha-blockade and ACE inhibition.
What to do
Start at a low dose with the patient seated or lying, and monitor blood pressure after initiation or dose increases.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Captopril
- Aliskiren + Captopril Contraindicated
- Captopril + Sacubitril / valsartan Contraindicated
- Captopril + Sacubitril-valsartan Contraindicated
- Amifostine + Captopril Major
- Amiloride + Captopril Major
- Amlodipine-hydrochlorothiazide-valsartan + Captopril Major
Frequently asked questions
Can I take Captopril with Moxisylyte?
MediHelp rates the interaction as moderate. Captopril and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxisylyte is an alpha-adrenergic blocker with vasodilating activity. With captopril, an exaggerated blood pressure drop may occur, particularly after the first dose.
How serious is the interaction between Captopril and Moxisylyte?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start at a low dose with the patient seated or lying, and monitor blood pressure after initiation or dose increases.
What other medicines interact with Captopril?
MediHelp also lists interactions of Captopril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Captopril page.
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