Drug interactions
Carbenoxolone + Formoterol
Severity: Moderate
Carbenoxolone and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum potassium. Carbenoxolone has mineralocorticoid-like activity that promotes potassium loss, and beta-2 agonists shift potassium into cells. Combined use may cause clinically significant hypokalemia, with a risk of arrhythmia, especially in patients with heart disease or on other potassium-wasting drugs.
What this interaction means in plain words
Carbenoxolone and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from carbenoxolone-induced renal potassium wasting and beta-2 mediated intracellular potassium shift by formoterol.
What to do
Monitor serum potassium at baseline and periodically during combined use, and replace potassium as needed. Take particular care in patients with cardiac disease or on other drugs that lower potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Carbenoxolone with Formoterol?
MediHelp rates the interaction as moderate. Carbenoxolone and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum potassium. Carbenoxolone has mineralocorticoid-like activity that promotes potassium loss, and beta-2 agonists shift potassium into cells. Combined use may cause clinically significant hypokalemia, with a risk of arrhythmia, especially in patients with heart disease or on other potassium-wasting drugs.
How serious is the interaction between Carbenoxolone and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium at baseline and periodically during combined use, and replace potassium as needed. Take particular care in patients with cardiac disease or on other drugs that lower potassium.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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