Drug interactions
Carbenoxolone + Terbutaline
Severity: Moderate
Carbenoxolone and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbenoxolone has mineralocorticoid-like activity that causes potassium loss, and terbutaline shifts potassium into cells. The combination can produce clinically relevant hypokalemia with arrhythmia risk.
What this interaction means in plain words
Carbenoxolone and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from renal potassium wasting (carbenoxolone) and beta-2 mediated intracellular potassium shift (terbutaline).
What to do
Monitor serum potassium and correct deficits, especially with high-dose terbutaline or concurrent diuretics.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Carbenoxolone with Terbutaline?
MediHelp rates the interaction as moderate. Carbenoxolone and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbenoxolone has mineralocorticoid-like activity that causes potassium loss, and terbutaline shifts potassium into cells. The combination can produce clinically relevant hypokalemia with arrhythmia risk.
How serious is the interaction between Carbenoxolone and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and correct deficits, especially with high-dose terbutaline or concurrent diuretics.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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