Drug interactions
Carbidopa-entacapone-levodopa + Iloprost inhaled
Severity: Minor
Carbidopa-entacapone-levodopa and Iloprost inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a prostacyclin vasodilator that can lower blood pressure, and levodopa therapy can contribute to hypotension. Systemic exposure from inhalation is modest, but additive effects on blood pressure are possible.
What this interaction means in plain words
Carbidopa-entacapone-levodopa and Iloprost inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive vasodilatory and hypotensive pharmacodynamic effects.
What to do
Monitor blood pressure and symptoms of dizziness or syncope when starting iloprost. No routine dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carbidopa-entacapone-levodopa
- Carbidopa-entacapone-levodopa + Isocarboxazid Contraindicated
- Carbidopa-entacapone-levodopa + Phenelzine Contraindicated
- Carbidopa-entacapone-levodopa + Selegiline transdermal Contraindicated
- Carbidopa-entacapone-levodopa + Tranylcypromine Contraindicated
- Amisulpride + Carbidopa-entacapone-levodopa Major
- Asenapine transdermal + Carbidopa-entacapone-levodopa Major
Frequently asked questions
Can I take Carbidopa-entacapone-levodopa with Iloprost inhaled?
MediHelp rates the interaction as minor. Carbidopa-entacapone-levodopa and Iloprost inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iloprost is a prostacyclin vasodilator that can lower blood pressure, and levodopa therapy can contribute to hypotension. Systemic exposure from inhalation is modest, but additive effects on blood pressure are possible.
How serious is the interaction between Carbidopa-entacapone-levodopa and Iloprost inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of dizziness or syncope when starting iloprost. No routine dose adjustment is needed.
What other medicines interact with Carbidopa-entacapone-levodopa?
MediHelp also lists interactions of Carbidopa-entacapone-levodopa with, for example, Isocarboxazid, Phenelzine, Selegiline transdermal. The full list is on the Carbidopa-entacapone-levodopa page.
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