Drug interactions
Carboplatin + Peramivir
Severity: Minor
Carboplatin and Peramivir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Peramivir is eliminated mainly by the kidneys, and carboplatin can impair renal function. Reduced kidney function may raise peramivir exposure, although the drug has a fairly wide safety margin.
What this interaction means in plain words
Carboplatin and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Carboplatin-related reduction in renal function may decrease renal clearance of peramivir.
What to do
Check creatinine clearance and adjust the peramivir dose to renal function as per labeling. Monitor for adverse effects such as diarrhea or neutropenia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carboplatin
Frequently asked questions
Can I take Carboplatin with Peramivir?
MediHelp rates the interaction as minor. Carboplatin and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Peramivir is eliminated mainly by the kidneys, and carboplatin can impair renal function. Reduced kidney function may raise peramivir exposure, although the drug has a fairly wide safety margin.
How serious is the interaction between Carboplatin and Peramivir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check creatinine clearance and adjust the peramivir dose to renal function as per labeling. Monitor for adverse effects such as diarrhea or neutropenia.
What other medicines interact with Carboplatin?
MediHelp also lists interactions of Carboplatin with, for example, Adenovirus types 4 and 7 live, Amikacin, Amphotericin b deoxycholate. The full list is on the Carboplatin page.
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