Drug interactions
Carvedilol + Ketorolac
Severity: Minor
Carvedilol and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac may reduce the blood pressure lowering effect of carvedilol, mainly with prolonged use. The effect is typically small.
What this interaction means in plain words
Carvedilol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carvedilol belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
Why it happens
NSAID inhibition of vasodilatory prostaglandins and fluid retention opposes the antihypertensive action of the beta-blocker.
What to do
Monitor blood pressure if ketorolac is continued beyond a few days. Adjust therapy if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Ketorolac?
MediHelp rates the interaction as minor. Carvedilol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ketorolac may reduce the blood pressure lowering effect of carvedilol, mainly with prolonged use. The effect is typically small.
How serious is the interaction between Carvedilol and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if ketorolac is continued beyond a few days. Adjust therapy if control is lost.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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