Drug interactions
Carvedilol + Telmisartan-amlodipine
Severity: Moderate
Carvedilol and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol adds to the antihypertensive effect of telmisartan and amlodipine, which may cause hypotension, dizziness or bradycardia. Potassium may rise slightly with beta-blockade and ARB therapy.
What this interaction means in plain words
Carvedilol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carvedilol belongs to Cardiovascular; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic blood pressure lowering, with alpha-blockade vasodilation from carvedilol.
What to do
Monitor blood pressure, heart rate and potassium, and titrate doses gradually.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Carvedilol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carvedilol adds to the antihypertensive effect of telmisartan and amlodipine, which may cause hypotension, dizziness or bradycardia. Potassium may rise slightly with beta-blockade and ARB therapy.
How serious is the interaction between Carvedilol and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and potassium, and titrate doses gradually.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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