Drug interactions
Carvedilol + Telmisartan
Severity: Moderate
Carvedilol and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so combined use can produce excess hypotension, especially at initiation or in volume-depleted patients. Beta-blockers can also modestly raise potassium, adding to the effect of an angiotensin receptor blocker.
What this interaction means in plain words
Carvedilol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carvedilol belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect; angiotensin receptor blockade reduces aldosterone-mediated potassium excretion and beta-blockade impairs cellular potassium uptake.
What to do
This combination is commonly used, for example in heart failure and hypertension. Monitor blood pressure, renal function and serum potassium after initiation and dose changes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carvedilol
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Carvedilol with Telmisartan?
MediHelp rates the interaction as moderate. Carvedilol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so combined use can produce excess hypotension, especially at initiation or in volume-depleted patients. Beta-blockers can also modestly raise potassium, adding to the effect of an angiotensin receptor blocker.
How serious is the interaction between Carvedilol and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: This combination is commonly used, for example in heart failure and hypertension. Monitor blood pressure, renal function and serum potassium after initiation and dose changes.
What other medicines interact with Carvedilol?
MediHelp also lists interactions of Carvedilol with, for example, Amifostine, Amiodarone, Arformoterol. The full list is on the Carvedilol page.
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