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Drug interactions

Celiprolol + Formoterol

Severity: Moderate

Celiprolol and Formoterol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Celiprolol is a beta-blocker with beta-1 selectivity and can blunt the bronchodilator effect of formoterol. This may reduce asthma or COPD control, and beta-blockade may leave patients less responsive to rescue beta-agonists. Celiprolol also has some partial beta-2 agonist activity, so the effect may be less than with other beta-blockers.

What this interaction means in plain words

Celiprolol and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Pharmacodynamic antagonism at beta-adrenergic receptors between the beta-blocker and the beta-2 agonist.

What to do

Monitor respiratory symptoms and lung function when the two are combined. Use only if the beta-blocker is clearly needed, and consider a non-beta-blocker alternative in patients with significant airway disease.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Celiprolol with Formoterol?

MediHelp rates the interaction as moderate. Celiprolol and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker with beta-1 selectivity and can blunt the bronchodilator effect of formoterol. This may reduce asthma or COPD control, and beta-blockade may leave patients less responsive to rescue beta-agonists. Celiprolol also has some partial beta-2 agonist activity, so the effect may be less than with other beta-blockers.

How serious is the interaction between Celiprolol and Formoterol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory symptoms and lung function when the two are combined. Use only if the beta-blocker is clearly needed, and consider a non-beta-blocker alternative in patients with significant airway disease.

What other medicines interact with Formoterol?

MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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