Drug interactions
Celiprolol + Hydrochlorothiazide-olmesartan
Severity: Minor
Celiprolol and Hydrochlorothiazide-olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol adds to blood pressure lowering, which may be useful but can cause excess hypotension. Hydrochlorothiazide, like some other thiazides, can reduce celiprolol absorption and exposure, which may diminish its effect.
What this interaction means in plain words
Celiprolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects, and reduced celiprolol absorption in the presence of the thiazide.
What to do
Monitor blood pressure and heart rate when starting the combination. Adjust the celiprolol dose if response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Frequently asked questions
Can I take Celiprolol with Hydrochlorothiazide-olmesartan?
MediHelp rates the interaction as minor. Celiprolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Celiprolol adds to blood pressure lowering, which may be useful but can cause excess hypotension. Hydrochlorothiazide, like some other thiazides, can reduce celiprolol absorption and exposure, which may diminish its effect.
How serious is the interaction between Celiprolol and Hydrochlorothiazide-olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting the combination. Adjust the celiprolol dose if response is inadequate.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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