Drug interactions
Celiprolol + Terbutaline
Severity: Moderate
Celiprolol and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a cardioselective beta-1 blocker with some beta-2 partial agonist activity, and may reduce the bronchodilator effect of terbutaline. Its airway effects are generally modest, but antagonism is possible in asthma or COPD.
What this interaction means in plain words
Celiprolol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta receptors, mainly at higher doses where selectivity is lost.
What to do
Monitor bronchodilator response and respiratory symptoms, and use the lowest effective celiprolol dose or an alternative antihypertensive in reactive airway disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Celiprolol with Terbutaline?
MediHelp rates the interaction as moderate. Celiprolol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a cardioselective beta-1 blocker with some beta-2 partial agonist activity, and may reduce the bronchodilator effect of terbutaline. Its airway effects are generally modest, but antagonism is possible in asthma or COPD.
How serious is the interaction between Celiprolol and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor bronchodilator response and respiratory symptoms, and use the lowest effective celiprolol dose or an alternative antihypertensive in reactive airway disease.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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