Drug interactions
Celiprolol + Theophylline
Severity: Minor
Celiprolol and Theophylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta blockers can oppose the bronchodilating effect of theophylline, and nonselective agents may also raise its levels. Celiprolol is beta-1 selective with partial beta-2 agonist activity, so the risk is lower than with nonselective drugs. Bronchospasm or theophylline toxicity is possible in susceptible patients.
What this interaction means in plain words
Celiprolol and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic antagonism at beta-receptors, with possible reduced theophylline metabolism.
What to do
Monitor respiratory status and theophylline levels when starting celiprolol in patients with airway disease. Prefer cardioselective agents and avoid nonselective ones.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Frequently asked questions
Can I take Celiprolol with Theophylline?
MediHelp rates the interaction as minor. Celiprolol and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Beta blockers can oppose the bronchodilating effect of theophylline, and nonselective agents may also raise its levels. Celiprolol is beta-1 selective with partial beta-2 agonist activity, so the risk is lower than with nonselective drugs. Bronchospasm or theophylline toxicity is possible in susceptible patients.
How serious is the interaction between Celiprolol and Theophylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory status and theophylline levels when starting celiprolol in patients with airway disease. Prefer cardioselective agents and avoid nonselective ones.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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