Drug interactions
Chasteberry + Pimozide
Severity: Minor
Chasteberry and Pimozide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chasteberry has dopaminergic activity that could in theory oppose the dopamine-blocking action of pimozide. No clinically meaningful interaction has been established.
What this interaction means in plain words
Chasteberry and Pimozide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism at dopamine D2 receptors; not firmly established.
What to do
Ask patients about herbal supplement use and watch for loss of symptom control if chasteberry is taken with pimozide. Stop the supplement if efficacy declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pimozide
- Adagrasib + Pimozide Contraindicated
- Amiodarone + Pimozide Contraindicated
- Amisulpride + Pimozide Contraindicated
- Amitriptyline + Pimozide Contraindicated
- Amoxapine + Pimozide Contraindicated
- Anagrelide + Pimozide Contraindicated
Frequently asked questions
Can I take Chasteberry with Pimozide?
MediHelp rates the interaction as minor. Chasteberry and Pimozide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chasteberry has dopaminergic activity that could in theory oppose the dopamine-blocking action of pimozide. No clinically meaningful interaction has been established.
How serious is the interaction between Chasteberry and Pimozide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal supplement use and watch for loss of symptom control if chasteberry is taken with pimozide. Stop the supplement if efficacy declines.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
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